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Exploration de la diversité fonctionnelle au sein d’une famille de métalloprotéines basée sur un repliement de type DSBH – CUPA
The cupin superfamily of proteins is one of the most functionally diverse family any described to date. It was named after the common structural core composed by eight '-strands folded into a distorte
Pontage covalent « clickable » optimisé pour la spectrométrie de masse, application à l’analyse structurale des pili de type IV de Neisseria meningitidis – CLICKMASSLINK
the expression of filamentous organelles called type IV pili. The basic component of these pili is a [...] this methodology will be the structural analysis of type IV pili virulence complex expressed by the bacterial [...] The application of our innovative cross-linkers to type IV pili of N. meningitidis will give us the unique
Développement de nouveaux équivalents synthétiques C1: sur la voie d'une chimie de type lego atomique – LEGO
(hydrogen, oxygen) into molecules coming from a vast types of reagents or catalysts is not a novel method, [...] reagents, are expected to easily react with various types of derivatives, and therefore be useful to extend
Polymérisation de systèmes supramoléculaires pour synthèse de type ‘template to template’ – T2T
Supramolecular self-assembly is a powerful tool in the control of nanometer structure formation for new materials functionalities. In macromolecular chemistry supramolecular organization has been stud